Content about Protease inhibitors

May 21, 2013

When boosting adherence means saving lives

More evidence is emerging that interventions by pharmacists can have a profound beneficial effect on patient outcomes.

The latest example comes from Walgreens Specialty Pharmacy, which released the results of a study May 17 showing that more than two-thirds of patients with hepatitis C “achieved sustained virologic response or cure after completing newer ‘triple therapy’ treatment” backed up by a regimen of care and oversight by pharmacists, according to a Drug Store News report from senior editor Michael Johnsen.

Why the pharmacist interventions? They help improve patient compliance with the complicated drug therapy, which involves the administration of two newer protease inhibitors to prevent the HCV virus from reproducing, in combination with peginterferon and ribavirin. According to Johnsen, that powerful medicinal cocktail “significantly increased the cure rate and cut treatment time in half” for the 406 HCV patients in the study who received triple therapy with either telaprevir or boceprevir.

May 17, 2013

Walgreens pharmacist interventions help improve compliance to newer 'triple therapy' hepatitis C treatment

More than two-thirds of patients with hepatitis C achieved sustained virologic response or cure after completing newer “triple therapy” treatment, according to a Walgreens Specialty Pharmacy study released Friday.

January 17, 2013

Boehringer Ingelheim Pharmaceuticals starts phase-3 trial of HCV drug

Boehringer Ingelheim Pharmaceuticals has enrolled the first patients in its late-stage trial of a treatment for hepatitis C, the drug maker said Thursday.

January 2, 2013

First anti-diarrheal drug for HIV/AIDS patients receives FDA approval

The U.S. Food and Drug Administration on Monday approved Fulyzaq (crofelemer) to relieve symptoms of diarrhea in HIV/AIDS patients taking antiretroviral therapy, a combination of medicines used to treat HIV infection.

November 12, 2012

FDA approves new strength of HIV drug

The Food and Drug Administration has approved a new strength of a drug for HIV made by Johnson & Johnson, the drug maker said.

June 29, 2012

Gilead seeks approval for HIV drug-boosting agent

Drug maker Gilead Sciences has submitted a regulatory approval application to the Food and Drug Administration for a drug designed to increase the blood levels of certain drugs for HIV.

May 14, 2012

FDA panel recommends approval for experimental Gilead HIV drug

A Food and Drug Administration expert panel has recommended approval of a drug made by Gilead Sciences for treating HIV, the drug maker said Friday.

December 20, 2011

WHO approves Mylan generic HIV drugs for use in developing world

The World Health Organization has approved three generic second-line treatments for HIV made by Mylan, the drug maker said Tuesday. The drugs will be delivered to people in developing countries living with HIV and AIDS.

December 2, 2011

Mylan generic drug for HIV/AIDS receives tentative FDA approval through PEPFAR

Under the President's Emergency Plan for AIDS Relief, the Food and Drug Administration has given tentative approval to a generic HIV and AIDS drug made by Mylan, the company said.

July 18, 2011

Minimal drug interaction found between Livalo, HIV drugs

A statin made by Eli Lilly and Kowa Pharmaceuticals America appears to work well with drugs used to treat HIV, according to a study presented at the sixth International AIDS Society conference on HIV Pathogenesis, Treatment and Prevention in Rome.

December 14, 2010

FDA approves revised dosage of HIV-combo drug

The Food and Drug Administration has approved a revised dosage for a drug combination, which includes a Johnson & Johnson drug, in HIV patients who have received treatment but whose virus has not become immune to the J&J drug.

October 20, 2010

Combining Invirase, Norvir could cause health problems

Combining two antiviral drugs for HIV may raise the risks of life-threatening heart problems, the...

October 4, 2010

Mylan subsidiary gets approval for HIV generic under PEPFAR

The Food and Drug Administration has approved a generic drug for HIV made by a...

February 22, 2010

Combined HIV drug therapy may cause heart rhythm issues

Combining two HIV drugs made by Roche subsidiary Genentech and Abbott could cause abnormalities in...

February 11, 2010

FDA approves new formulation of HIV treatment drug

The Food and Drug Administration has approved a new formulation of an anti-retroviral drug for...