Herb works as anti-ulcer therapy, study shows

BEIJING A research team led by Syed Rafatullah from Saudi Arabia validated the gastric anti-ulcer properties of the herb Rocket “Eruca sativa L.” (EER) on experimentally-induced gastric secretion and ulceration in albino rats. The study was published April 28 in the World Journal of Gastroenterology.

In recent years, Rocket "Eruca sativa L." (EER), a member of the Brassicacae family, has gained greater importance as a salad vegetable and spice, especially among Middle Eastern populations and Europeans. It is believed that plants belonging to the Brassicacae family possess diversified medicinal and therapeutic properties including inhibition of tumorigenesis, anti-ulcer and hepatoprotective activities.

Although the introduction of proton-pump inhibitors to the classic anti-ulcer therapy has revolutionized treatment of peptic ulcers and other gastrointestinal disorders, there is still no complete cure for this disease, researchers noted. It has been shown that long term use of these drugs leads to various adverse and side effects. Relapses of the malady, ineffectiveness of different drug regimens and even resistance to drugs are emerging. Thus, there is an urgent requirement to identify more effective and safe anti-ulcer agents.

Researchers found that the ethanolic extract of EER significantly and dose-dependently reduced basal gastric acid secretion, titratable acidity and ruminal ulceration in lab rats. The authors concluded that EER extract possesses anti-ulcer activities against experimentally-induced gastric lesions.

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