COLLEGEVILLE, Pa. A study published in the July/August issue of Menopause: The Journal of the North American Menopause Society supported daily and twice-weekly use of Premarin (conjugated estrogens) Vaginal Cream to relieve symptoms of moderate-to-severe vulvar and vaginal atrophy, including painful intercourse, Wyeth Pharmaceuticals announced Monday.
In this study, dyspareunia (painful intercourse) was the most bothersome symptom at baseline (57%) followed by vaginal dryness, itching and burning. Unlike hot flashes or night sweats, signs and symptoms of vaginal atrophy have been shown to increase over time in postmenopausal women.
“Based on market research data, we understand that many postmenopausal women are not discussing their symptoms with their health care professionals,” stated Gloria Bachmann, lead study author and director of the Women’s Health Institute at the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School. “We are encouraged by this 52-week data that showed twice-weekly use of Premarin Vaginal Cream was sufficient to provide relief from painful intercourse due to menopause. The study also supported daily use of Premarin Vaginal Cream 0.5 g to treat postmenopausal vaginal dryness. This information should aid postmenopausal women and their health care professionals in discussing whether and how they may treat vaginal atrophy.”