Pfizer discontinues phase 3 trial of axitinib as treatment for pancreatic cancer

2/2/2009

NEW YORK Pfizer has discontinued a phase 3 trial of a drug it was investigating as a treatment for pancreatic cancer, the drug maker announced Friday.

The company said an investigative board found no evidence that patients treated with axitinib and gemcitabine did better than those treated with gemcitabine alone. Gemcitabine is a standard treatment for pancreatic cancer.

"These results were disappointing, given the trend towards prolonged survival seen in a phase 2 study of axitinib in this extremely difficult-to-treat patient population," Pfizer Oncology Business Unit's SVP clinical development and medical affairs Mace Rothenberg stated. "However, we remain steadfastly committed to continued investigation of axitinib in renal cell carcinoma, where it is currently in phase 3 for second-line treatment."

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