WHAT IT MEANS AND WHY IT'S IMPORTANT It has been coined "The Oprah Effect" and it is the notion that if you're lucky enough to get a thumbs up by Oprah on "The Oprah Winfrey Show," her viewers will heed her call and run -- not walk -- to buy your product or services. Walgreens and its Take Care Clinic business are among the latest to be graced with the icon's million-dollar touch.