Next generation of wearable diagnostics designed for continual monitoring

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Next generation of wearable diagnostics designed for continual monitoring

By Michael Johnsen - 07/21/2017

TOKYO — Improvements are being made around wearable diagnostics that can monitor one of several vital health signs. The University of Tokyo is currently developing a hypoallergenic electronic sensor that can be worn on the skin continuously for a week without discomfort and is so light and thin that users forget they even have it on.

The elastic electrode constructed of breathable nanoscale meshes holds promise for the development of noninvasive e-skin devices that can monitor a person's health continuously over a long period, the researchers reported.

Wearable electronics that monitor heart rate and other vital health signals have made headway in recent years, with next-generation gadgets employing lightweight, highly elastic materials attached directly onto the skin for more sensitive, precise measurements. However, although the ultrathin films and rubber sheets used in these devices adhere and conform well to the skin, their lack of breathability is deemed unsafe for long-term use: dermatological tests show the fine, stretchable materials prevent sweating and block airflow around the skin, causing irritation and inflammation, which ultimately could lead to lasting physiological and psychological effects.

"We learned that devices that can be worn for a week or longer for continuous monitoring were needed for practical use in medical and sports applications," stated professor Takao Someya at the University of Tokyo's Graduate School of Engineering whose research group had previously developed an on-skin patch that measured oxygen in blood.

In the current research, the group developed an electrode constructed from nanoscale meshes containing a water-soluble polymer, polyvinyl alcohol and a gold layer, all materials considered safe and biologically compatible with the body. The device can be applied by spraying a tiny amount of water, which dissolves the PVA nanofibers and allows it to stick easily to the skin. It conformed seamlessly to curvilinear surfaces of human skin, such as sweat pores and the ridges of an index finger's fingerprint pattern.

The researchers next conducted a skin patch test on 20 subjects and detected no inflammation on the participants' skin after they had worn the device for a week. The group also evaluated the permeability, with water vapor, of the nanomesh conductor, along with those of other substrates like ultrathin plastic foil and a thin rubber sheet, and found that its porous mesh structure exhibited superior gas permeability compared to that of the other materials.

"It will become possible to monitor patients' vital signs without causing any stress or discomfort," Someya said, regarding the future implications of the team's research. In addition to nursing care and medical applications, the new device promises to enable continuous, precise monitoring of athletes' physiological signals and bodily motion without impeding their training or performance.


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